Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Frontier Airlines

The cheapest airline(s) flying from Saint Louis to San Diego is Frontier Airlines.

  • Frontier Airlines Frontier Airlines
  • United Airlines United Airlines
  • American Airlines American Airlines
  • Southwest Airlines Southwest Airlines
  • Alaska Airlines Alaska Airlines
Cheapest Month December

Travel Period: December 2024 - November 2025

The cheapest month(s) to fly from Saint Louis to San Diego is December.

  • Dec 2024
  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
Cheapest Day of the Week Monday

The cheapest day(s) of the week to fly from Saint Louis to San Diego is Monday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Sat, 2 Nov, 2024

  • Time Earliest
    • Earliest
    • Latest
  • Depart Earliest
    • Earliest
    • Latest
  • Arrive
    • Earliest
    • Latest
  • Duration
    • Shortest
    • Longest
  • Stopover
    All
    • Airline Filter by Airline
      View All Airline
      • Availability
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 18:15 STL
        20:20 SAN
        4Hrs, 05m Direct
      • STLSt Louis Lambert Intl Airport 18:15 - SAN 20:20 4h 05m Direct
      • STLSt Louis Lambert Intl Airport 18:15
      • SANSan Diego International Airport 20:20
      • 4h 05m
      • Direct
      • Southwest Airlines (WN 564)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 564)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 Max 8 Passenger
      • 18:45 STL
        22:05 SAN
        5Hrs, 20m Direct
      • STLSt Louis Lambert Intl Airport 18:45 - SAN 22:05 5h 20m Direct
      • STLSt Louis Lambert Intl Airport 18:45
      • SANSan Diego International Airport 22:05
      • 5h 20m
      • Direct
      • Southwest Airlines (WN 3241)Boeing 737 700
      • Southwest Airlines (WN 3241)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • Boeing 737 700
      • 19:00 STL
        21:00 SAN
        4Hrs, 00m Direct
      • STLSt Louis Lambert Intl Airport 19:00 - SAN 21:00 4h Direct
      • STLSt Louis Lambert Intl Airport 19:00
      • SANSan Diego International Airport 21:00
      • 4h
      • Direct
      • Southwest Airlines (WN 1424)Boeing 737 700
      • Southwest Airlines (WN 1424)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • Boeing 737 700
      • 19:30 STL
        23:00 SAN
        5Hrs, 30m Direct
      • STLSt Louis Lambert Intl Airport 19:30 - SAN 23:00 5h 30m Direct
      • STLSt Louis Lambert Intl Airport 19:30
      • SANSan Diego International Airport 23:00
      • 5h 30m
      • Direct
      • Southwest Airlines (WN 3529)Boeing 737 700
      • Southwest Airlines (WN 3529)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 700
      • 20:05 STL
        22:05 SAN
        4Hrs, 00m Direct
      • STLSt Louis Lambert Intl Airport 20:05 - SAN 22:05 4h Direct
      • STLSt Louis Lambert Intl Airport 20:05
      • SANSan Diego International Airport 22:05
      • 4h
      • Direct
      • Southwest Airlines (WN 4198)Boeing 737 700
      • Southwest Airlines (WN 4198)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • Boeing 737 700
      • 20:55 STL
        22:55 SAN
        4Hrs, 00m Direct
      • STLSt Louis Lambert Intl Airport 20:55 - SAN 22:55 4h Direct
      • STLSt Louis Lambert Intl Airport 20:55
      • SANSan Diego International Airport 22:55
      • 4h
      • Direct
      • Southwest Airlines (WN 2098)Boeing 737 700
      • Southwest Airlines (WN 2098)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • Boeing 737 700
      • 06:30 STL
        08:35 SAN
        4Hrs, 05m Direct
      • STLSt Louis Lambert Intl Airport 06:30 - SAN 08:35 4h 05m Direct
      • STLSt Louis Lambert Intl Airport 06:30
      • SANSan Diego International Airport 08:35
      • 4h 05m
      • Direct
      • Southwest Airlines (WN 1988)Boeing 737 700
      • Southwest Airlines (WN 1988)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • Boeing 737 700
      • 07:15 STL
        09:20 SAN
        4Hrs, 05m Direct
      • STLSt Louis Lambert Intl Airport 07:15 - SAN 09:20 4h 05m Direct
      • STLSt Louis Lambert Intl Airport 07:15
      • SANSan Diego International Airport 09:20
      • 4h 05m
      • Direct
      • Southwest Airlines (WN 4178)Boeing 737 700
      • Southwest Airlines (WN 4178)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 700
      • 07:45 STL
        14:15 SAN
        8Hrs, 30m Direct
      • STLSt Louis Lambert Intl Airport 07:45 - SAN 14:15 8h 30m Direct
      • STLSt Louis Lambert Intl Airport 07:45
      • SANSan Diego International Airport 14:15
      • 8h 30m
      • Direct
      • Southwest Airlines (WN 2554)Boeing 737 700
      • Southwest Airlines (WN 2554)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 700
      • 09:50 STL
        11:55 SAN
        4Hrs, 05m Direct
      • STLSt Louis Lambert Intl Airport 09:50 - SAN 11:55 4h 05m Direct
      • STLSt Louis Lambert Intl Airport 09:50
      • SANSan Diego International Airport 11:55
      • 4h 05m
      • Direct
      • Southwest Airlines (WN 4339)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 4339)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • Boeing 737 Max 8 Passenger
      • 09:50 STL
        11:55 SAN
        4Hrs, 05m Direct
      • STLSt Louis Lambert Intl Airport 09:50 - SAN 11:55 4h 05m Direct
      • STLSt Louis Lambert Intl Airport 09:50
      • SANSan Diego International Airport 11:55
      • 4h 05m
      • Direct
      • Southwest Airlines (WN 3010)Boeing 737 700
      • Southwest Airlines (WN 3010)
        • -
        • -
        • -
        • T
        • -
        • -
        • -
      • Boeing 737 700
      • 09:55 STL
        12:00 SAN
        4Hrs, 05m Direct
      • STLSt Louis Lambert Intl Airport 09:55 - SAN 12:00 4h 05m Direct
      • STLSt Louis Lambert Intl Airport 09:55
      • SANSan Diego International Airport 12:00
      • 4h 05m
      • Direct
      • Southwest Airlines (WN 4499)Boeing 737 700
      • Southwest Airlines (WN 4499)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • Boeing 737 700
      • 09:55 STL
        15:05 SAN
        7Hrs, 10m Direct
      • STLSt Louis Lambert Intl Airport 09:55 - SAN 15:05 7h 10m Direct
      • STLSt Louis Lambert Intl Airport 09:55
      • SANSan Diego International Airport 15:05
      • 7h 10m
      • Direct
      • Southwest Airlines (WN 1091)Boeing 737 800
      • Southwest Airlines (WN 1091)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 800
      • 10:10 STL
        13:35 SAN
        5Hrs, 25m Direct
      • STLSt Louis Lambert Intl Airport 10:10 - SAN 13:35 5h 25m Direct
      • STLSt Louis Lambert Intl Airport 10:10
      • SANSan Diego International Airport 13:35
      • 5h 25m
      • Direct
      • Southwest Airlines (WN 1401)Boeing 737 700
      • Southwest Airlines (WN 1401)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • Boeing 737 700
      • 10:55 STL
        17:20 SAN
        8Hrs, 25m Direct
      • STLSt Louis Lambert Intl Airport 10:55 - SAN 17:20 8h 25m Direct
      • STLSt Louis Lambert Intl Airport 10:55
      • SANSan Diego International Airport 17:20
      • 8h 25m
      • Direct
      • Southwest Airlines (WN 2364)Boeing 737 700
      • Southwest Airlines (WN 2364)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 700
      • 11:00 STL
        13:00 SAN
        4Hrs, 00m Direct
      • STLSt Louis Lambert Intl Airport 11:00 - SAN 13:00 4h Direct
      • STLSt Louis Lambert Intl Airport 11:00
      • SANSan Diego International Airport 13:00
      • 4h
      • Direct
      • Southwest Airlines (WN 3648)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 3648)
        • -
        • -
        • -
        • -
        • F
        • -
        • -
      • Boeing 737 Max 8 Passenger
      • 13:25 STL
        16:55 SAN
        5Hrs, 30m Direct
      • STLSt Louis Lambert Intl Airport 13:25 - SAN 16:55 5h 30m Direct
      • STLSt Louis Lambert Intl Airport 13:25
      • SANSan Diego International Airport 16:55
      • 5h 30m
      • Direct
      • Southwest Airlines (WN 1186)Boeing 737 700
      • Southwest Airlines (WN 1186)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • Boeing 737 700
      • 14:25 STL
        17:50 SAN
        5Hrs, 25m Direct
      • STLSt Louis Lambert Intl Airport 14:25 - SAN 17:50 5h 25m Direct
      • STLSt Louis Lambert Intl Airport 14:25
      • SANSan Diego International Airport 17:50
      • 5h 25m
      • Direct
      • Southwest Airlines (WN 695)Boeing 737 800
      • Southwest Airlines (WN 695)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • Boeing 737 800
      • 18:10 STL
        22:20 SAN
        6Hrs, 10m 1 Stop (PHX)
      • STLSt Louis Lambert Intl Airport 18:10 - SAN 22:20 6h 10m 1 Stop (PHX) Phoenix
      • STLSt Louis Lambert Intl Airport 18:10
        PHXPhoenix Sky Harbor Intl Airport 22:05
      • PHXPhoenix Sky Harbor Intl Airport 20:35
        SANSan Diego International Airport 22:20
      • 6h 10m (1h 30m)
      • 1 Stop PHX · Phoenix 1h 30m
      • Southwest Airlines (WN 5122)Boeing 737 700
        Southwest Airlines (WN 3735)Boeing 737 700
      • Southwest Airlines (WN 5122)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 18:10 STL
        22:50 SAN
        6Hrs, 40m 1 Stop (MDW)
      • STLSt Louis Lambert Intl Airport 18:10 - SAN 22:50 6h 40m 1 Stop (MDW) Chicago
      • STLSt Louis Lambert Intl Airport 18:10
        MDWChicago Midway Airport 20:25
      • MDWChicago Midway Airport 19:20
        SANSan Diego International Airport 22:50
      • 6h 40m (1h 05m)
      • 1 Stop MDW · Chicago 1h 05m
      • Southwest Airlines (WN 1253)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 2707)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 1253)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 18:20 STL
        22:40 SAN
        6Hrs, 20m 1 Stop (DAL)
      • STLSt Louis Lambert Intl Airport 18:20 - SAN 22:40 6h 20m 1 Stop (DAL) Dallas
      • STLSt Louis Lambert Intl Airport 18:20
        DALDallas/Fort Worth Love Field Airport 21:30
      • DALDallas/Fort Worth Love Field Airport 20:10
        SANSan Diego International Airport 22:40
      • 6h 20m (1h 20m)
      • 1 Stop DAL · Dallas 1h 20m
      • Southwest Airlines (WN 1592)Boeing 737 800
        Southwest Airlines (WN 840)Boeing 737 700
      • Southwest Airlines (WN 1592)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 18:25 STL
        23:25 SAN
        7Hrs, 00m 1 Stop (DEN)
      • STLSt Louis Lambert Intl Airport 18:25 - SAN 23:25 7h 1 Stop (DEN) Denver
      • STLSt Louis Lambert Intl Airport 18:25
        DENDenver Intl Airport 22:00
      • DENDenver Intl Airport 19:50
        SANSan Diego International Airport 23:25
      • 7h (2h 10m)
      • 1 Stop DEN · Denver 2h 10m
      • Southwest Airlines (WN 3529)Boeing 737 700
        Southwest Airlines (WN 1669)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 3529)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 18:30 STL
        22:05 SAN
        5Hrs, 35m 1 Stop (LAS)
      • STLSt Louis Lambert Intl Airport 18:30 - SAN 22:05 5h 35m 1 Stop (LAS) Las Vegas
      • STLSt Louis Lambert Intl Airport 18:30
        LASLas Vegas McCarran International Airport 20:55
      • LASLas Vegas McCarran International Airport 20:05
        SANSan Diego International Airport 22:05
      • 5h 35m (50m)
      • 1 Stop LAS · Las Vegas 50m
      • Southwest Airlines (WN 3603)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 4098)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 3603)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 18:40 STL
        22:30 SAN
        5Hrs, 50m 1 Stop (LAS)
      • STLSt Louis Lambert Intl Airport 18:40 - SAN 22:30 5h 50m 1 Stop (LAS) Las Vegas
      • STLSt Louis Lambert Intl Airport 18:40
        LASLas Vegas McCarran International Airport 21:20
      • LASLas Vegas McCarran International Airport 20:15
        SANSan Diego International Airport 22:30
      • 5h 50m (1h 05m)
      • 1 Stop LAS · Las Vegas 1h 05m
      • Southwest Airlines (WN 863)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 4098)Boeing 737 700
      • Southwest Airlines (WN 863)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 18:45 STL
        23:10 SAN
        6Hrs, 25m 1 Stop (LAS)
      • STLSt Louis Lambert Intl Airport 18:45 - SAN 23:10 6h 25m 1 Stop (LAS) Las Vegas
      • STLSt Louis Lambert Intl Airport 18:45
        LASLas Vegas McCarran International Airport 22:00
      • LASLas Vegas McCarran International Airport 20:20
        SANSan Diego International Airport 23:10
      • 6h 25m (1h 40m)
      • 1 Stop LAS · Las Vegas 1h 40m
      • Southwest Airlines (WN 3241)Boeing 737 700
        Southwest Airlines (WN 1393)Boeing 737 700
      • Southwest Airlines (WN 3241)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 19:00 STL
        23:25 SAN
        6Hrs, 25m 1 Stop (HOU)
      • STLSt Louis Lambert Intl Airport 19:00 - SAN 23:25 6h 25m 1 Stop (HOU) Houston
      • STLSt Louis Lambert Intl Airport 19:00
        HOUHouston Hobby Airport 21:55
      • HOUHouston Hobby Airport 21:15
        SANSan Diego International Airport 23:25
      • 6h 25m (40m)
      • 1 Stop HOU · Houston 40m
      • Southwest Airlines (WN 4083)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 4933)Boeing 737 700
      • Southwest Airlines (WN 4083)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 19:10 STL
        23:05 SAN
        5Hrs, 55m 1 Stop (DEN)
      • STLSt Louis Lambert Intl Airport 19:10 - SAN 23:05 5h 55m 1 Stop (DEN) Denver
      • STLSt Louis Lambert Intl Airport 19:10
        DENDenver Intl Airport 21:40
      • DENDenver Intl Airport 20:35
        SANSan Diego International Airport 23:05
      • 5h 55m (1h 05m)
      • 1 Stop DEN · Denver 1h 05m
      • Southwest Airlines (WN 3529)Boeing 737 700
        Southwest Airlines (WN 1669)Boeing 737 800
      • Southwest Airlines (WN 3529)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 19:10 STL
        23:25 SAN
        6Hrs, 15m 1 Stop (DEN)
      • STLSt Louis Lambert Intl Airport 19:10 - SAN 23:25 6h 15m 1 Stop (DEN) Denver
      • STLSt Louis Lambert Intl Airport 19:10
        DENDenver Intl Airport 22:00
      • DENDenver Intl Airport 20:35
        SANSan Diego International Airport 23:25
      • 6h 15m (1h 25m)
      • 1 Stop DEN · Denver 1h 25m
      • Southwest Airlines (WN 956)Boeing 737 800
        Southwest Airlines (WN 2144)Boeing 737 700
      • Southwest Airlines (WN 956)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 19:10 STL
        23:25 SAN
        6Hrs, 15m 1 Stop (DAL)
      • STLSt Louis Lambert Intl Airport 19:10 - SAN 23:25 6h 15m 1 Stop (DAL) Dallas
      • STLSt Louis Lambert Intl Airport 19:10
        DALDallas/Fort Worth Love Field Airport 22:15
      • DALDallas/Fort Worth Love Field Airport 20:55
        SANSan Diego International Airport 23:25
      • 6h 15m (1h 20m)
      • 1 Stop DAL · Dallas 1h 20m
      • Southwest Airlines (WN 2437)Boeing 737 800
        Southwest Airlines (WN 3961)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 2437)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 19:20 STL
        23:10 SAN
        5Hrs, 50m 1 Stop (DAL)
      • STLSt Louis Lambert Intl Airport 19:20 - SAN 23:10 5h 50m 1 Stop (DAL) Dallas
      • STLSt Louis Lambert Intl Airport 19:20
        DALDallas/Fort Worth Love Field Airport 22:00
      • DALDallas/Fort Worth Love Field Airport 21:05
        SANSan Diego International Airport 23:10
      • 5h 50m (55m)
      • 1 Stop DAL · Dallas 55m
      • Southwest Airlines (WN 2655)Boeing 737 800
        Southwest Airlines (WN 671)Boeing 737 700
      • Southwest Airlines (WN 2655)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 19:30 STL
        23:58 SAN
        6Hrs, 28m 1 Stop (DFW)
      • STLSt Louis Lambert Intl Airport 19:30 - SAN 23:58 6h 28m 1 Stop (DFW) Dallas
      • STLSt Louis Lambert Intl Airport 19:30
        DFWDallas/Fort Worth Intl Airport 22:45
      • DFWDallas/Fort Worth Intl Airport 21:34
        SANSan Diego International Airport 23:58
      • 6h 28m (1h 11m)
      • 1 Stop DFW · Dallas 1h 11m
      • American Airlines (AA 2013)Boeing 737 800
        American Airlines (AA 2568)Airbus
      • American Airlines (AA 2013)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 20:30 STL
        00:06 SAN
        5Hrs, 36m 1 Stop (PHX)
      • STLSt Louis Lambert Intl Airport 20:30 - SAN 00:06 5h 36m 1 Stop (PHX) Phoenix
      • STLSt Louis Lambert Intl Airport 20:30
        PHXPhoenix Sky Harbor Intl Airport 23:50
      • PHXPhoenix Sky Harbor Intl Airport 22:57
        SANSan Diego International Airport 00:06
      • 5h 36m (53m)
      • 1 Stop PHX · Phoenix 53m
      • American Airlines (AA 6209)Crj 700 Canadair Regional
        American Airlines (AA 2983)Airbus
      • American Airlines (AA 6209)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 21:44 STL
        01:27 SAN
        5Hrs, 43m 1 Stop (DEN)
      • STLSt Louis Lambert Intl Airport 21:44 - SAN 01:27 5h 43m 1 Stop (DEN) Denver
      • STLSt Louis Lambert Intl Airport 21:44
        DENDenver Intl Airport 23:59
      • DENDenver Intl Airport 23:15
        SANSan Diego International Airport 01:27
      • 5h 43m (44m)
      • 1 Stop DEN · Denver 44m
      • United Airlines (UA 1083)Airbus
        United Airlines (UA 1055)Boeing 737 800
      • United Airlines (UA 1083)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 05:00 STL
        11:08 SAN
        8Hrs, 08m 1 Stop (CLT)
      • STLSt Louis Lambert Intl Airport 05:00 - SAN 11:08 8h 08m 1 Stop (CLT) Charlotte
      • STLSt Louis Lambert Intl Airport 05:00
        CLTCharlotte Airport 08:55
      • CLTCharlotte Airport 07:56
        SANSan Diego International Airport 11:08
      • 8h 08m (59m)
      • 1 Stop CLT · Charlotte 59m
      • American Airlines (AA 1515)Boeing 737 800
        American Airlines (AA 1954)Airbus
      • American Airlines (AA 1515)
        • M
        • T
        • W
        • -
        • F
        • S
        • S
      • 05:00 STL
        11:10 SAN
        8Hrs, 10m 1 Stop (PHX)
      • STLSt Louis Lambert Intl Airport 05:00 - SAN 11:10 8h 10m 1 Stop (PHX) Phoenix
      • STLSt Louis Lambert Intl Airport 05:00
        PHXPhoenix Sky Harbor Intl Airport 10:55
      • PHXPhoenix Sky Harbor Intl Airport 07:35
        SANSan Diego International Airport 11:10
      • 8h 10m (3h 20m)
      • 1 Stop PHX · Phoenix 3h 20m
      • Southwest Airlines (WN 2991)Boeing 737 800
        Southwest Airlines (WN 1785)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 2991)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 05:10 STL
        11:15 SAN
        8Hrs, 05m 1 Stop (PHX)
      • STLSt Louis Lambert Intl Airport 05:10 - SAN 11:15 8h 05m 1 Stop (PHX) Phoenix
      • STLSt Louis Lambert Intl Airport 05:10
        PHXPhoenix Sky Harbor Intl Airport 11:00
      • PHXPhoenix Sky Harbor Intl Airport 07:45
        SANSan Diego International Airport 11:15
      • 8h 05m (3h 15m)
      • 1 Stop PHX · Phoenix 3h 15m
      • Southwest Airlines (WN 2991)Boeing 737 700
        Southwest Airlines (WN 422)Boeing 737 700
      • Southwest Airlines (WN 2991)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 05:10 STL
        08:55 SAN
        5Hrs, 45m 1 Stop (PHX)
      • STLSt Louis Lambert Intl Airport 05:10 - SAN 08:55 5h 45m 1 Stop (PHX) Phoenix
      • STLSt Louis Lambert Intl Airport 05:10
        PHXPhoenix Sky Harbor Intl Airport 08:35
      • PHXPhoenix Sky Harbor Intl Airport 07:45
        SANSan Diego International Airport 08:55
      • 5h 45m (50m)
      • 1 Stop PHX · Phoenix 50m
      • Southwest Airlines (WN 2991)Boeing 737 700
        Southwest Airlines (WN 649)Boeing 737 700
      • Southwest Airlines (WN 2991)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 05:15 STL
        10:05 SAN
        6Hrs, 50m 1 Stop (DEN)
      • STLSt Louis Lambert Intl Airport 05:15 - SAN 10:05 6h 50m 1 Stop (DEN) Denver
      • STLSt Louis Lambert Intl Airport 05:15
        DENDenver Intl Airport 08:40
      • DENDenver Intl Airport 06:45
        SANSan Diego International Airport 10:05
      • 6h 50m (1h 55m)
      • 1 Stop DEN · Denver 1h 55m
      • Southwest Airlines (WN 2596)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 6481)Boeing 737 700
      • Southwest Airlines (WN 2596)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 05:15 STL
        11:30 SAN
        8Hrs, 15m 1 Stop (DEN)
      • STLSt Louis Lambert Intl Airport 05:15 - SAN 11:30 8h 15m 1 Stop (DEN) Denver
      • STLSt Louis Lambert Intl Airport 05:15
        DENDenver Intl Airport 10:00
      • DENDenver Intl Airport 06:45
        SANSan Diego International Airport 11:30
      • 8h 15m (3h 15m)
      • 1 Stop DEN · Denver 3h 15m
      • Southwest Airlines (WN 2596)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 1987)Boeing 737 700
      • Southwest Airlines (WN 2596)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 05:17 STL
        12:40 SAN
        9Hrs, 23m 1 Stop (DFW)
      • STLSt Louis Lambert Intl Airport 05:17 - SAN 12:40 9h 23m 1 Stop (DFW) Dallas
      • STLSt Louis Lambert Intl Airport 05:17
        DFWDallas/Fort Worth Intl Airport 11:27
      • DFWDallas/Fort Worth Intl Airport 07:19
        SANSan Diego International Airport 12:40
      • 9h 23m (4h 08m)
      • 1 Stop DFW · Dallas 4h 08m
      • American Airlines (AA 2261)Airbus
        American Airlines (AA 1055)Airbus
      • American Airlines (AA 2261)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 05:17 STL
        10:08 SAN
        6Hrs, 51m 1 Stop (DFW)
      • STLSt Louis Lambert Intl Airport 05:17 - SAN 10:08 6h 51m 1 Stop (DFW) Dallas
      • STLSt Louis Lambert Intl Airport 05:17
        DFWDallas/Fort Worth Intl Airport 08:50
      • DFWDallas/Fort Worth Intl Airport 07:19
        SANSan Diego International Airport 10:08
      • 6h 51m (1h 31m)
      • 1 Stop DFW · Dallas 1h 31m
      • American Airlines (AA 2261)Airbus
        American Airlines (AA 384)Airbus
      • American Airlines (AA 2261)
        • M
        • T
        • W
        • -
        • -
        • S
        • S
      • 05:17 STL
        10:09 SAN
        6Hrs, 52m 1 Stop (DFW)
      • STLSt Louis Lambert Intl Airport 05:17 - SAN 10:09 6h 52m 1 Stop (DFW) Dallas
      • STLSt Louis Lambert Intl Airport 05:17
        DFWDallas/Fort Worth Intl Airport 08:50
      • DFWDallas/Fort Worth Intl Airport 07:19
        SANSan Diego International Airport 10:09
      • 6h 52m (1h 31m)
      • 1 Stop DFW · Dallas 1h 31m
      • American Airlines (AA 2261)Airbus
        American Airlines (AA 384)Airbus
      • American Airlines (AA 2261)
        • -
        • -
        • -
        • T
        • -
        • -
        • -
      • 05:17 STL
        10:09 SAN
        6Hrs, 52m 1 Stop (DFW)
      • STLSt Louis Lambert Intl Airport 05:17 - SAN 10:09 6h 52m 1 Stop (DFW) Dallas
      • STLSt Louis Lambert Intl Airport 05:17
        DFWDallas/Fort Worth Intl Airport 08:50
      • DFWDallas/Fort Worth Intl Airport 07:19
        SANSan Diego International Airport 10:09
      • 6h 52m (1h 31m)
      • 1 Stop DFW · Dallas 1h 31m
      • American Airlines (AA 2261)Airbus
        American Airlines (AA 384)Boeing 737 800
      • American Airlines (AA 2261)
        • -
        • -
        • -
        • -
        • F
        • -
        • -
      • 05:30 STL
        10:30 SAN
        7Hrs, 00m 1 Stop (MDW)
      • STLSt Louis Lambert Intl Airport 05:30 - SAN 10:30 7h 1 Stop (MDW) Chicago
      • STLSt Louis Lambert Intl Airport 05:30
        MDWChicago Midway Airport 08:00
      • MDWChicago Midway Airport 06:40
        SANSan Diego International Airport 10:30
      • 7h (1h 20m)
      • 1 Stop MDW · Chicago 1h 20m
      • Southwest Airlines (WN 367)Boeing 737 700
        Southwest Airlines (WN 1738)Boeing 737 700
      • Southwest Airlines (WN 367)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 09:55 LAS
        07:00 DEN
        7Hrs, 40m 1 Stop (SAN)
      • LASLas Vegas McCarran International Airport 09:55 - DEN 07:00 7h 40m 1 Stop (SAN) San Diego
      • LASLas Vegas McCarran International Airport 09:55
        STLSt Louis Lambert Intl Airport 05:30
      • SANSan Diego International Airport 11:10
        DENDenver Intl Airport 07:00
      • 7h 40m (1h 50m)
      • 1 Stop SAN · San Diego 1h 50m
      • Southwest Airlines (WN 1542)Boeing 737 700
        Southwest Airlines (WN 4221)Boeing 737 700
      • Southwest Airlines (WN 1542)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 05:30 STL
        11:10 SAN
        7Hrs, 40m 1 Stop (DEN)
      • STLSt Louis Lambert Intl Airport 05:30 - SAN 11:10 7h 40m 1 Stop (DEN) Denver
      • STLSt Louis Lambert Intl Airport 05:30
        DENDenver Intl Airport 09:45
      • DENDenver Intl Airport 07:00
        SANSan Diego International Airport 11:10
      • 7h 40m (2h 45m)
      • 1 Stop DEN · Denver 2h 45m
      • Southwest Airlines (WN 4221)Boeing 737 700
        Southwest Airlines (WN 3547)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 4221)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 05:30 STL
        12:00 SAN
        8Hrs, 30m 1 Stop (DAL)
      • STLSt Louis Lambert Intl Airport 05:30 - SAN 12:00 8h 30m 1 Stop (DAL) Dallas
      • STLSt Louis Lambert Intl Airport 05:30
        DALDallas/Fort Worth Love Field Airport 10:45
      • DALDallas/Fort Worth Love Field Airport 07:20
        SANSan Diego International Airport 12:00
      • 8h 30m (3h 25m)
      • 1 Stop DAL · Dallas 3h 25m
      • Southwest Airlines (WN 1703)Boeing 737 700
        Southwest Airlines (WN 2543)Boeing 737 800
      • Southwest Airlines (WN 1703)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 05:35 STL
        09:25 SAN
        5Hrs, 50m 1 Stop (LAS)
      • STLSt Louis Lambert Intl Airport 05:35 - SAN 09:25 5h 50m 1 Stop (LAS) Las Vegas
      • STLSt Louis Lambert Intl Airport 05:35
        LASLas Vegas McCarran International Airport 08:10
      • LASLas Vegas McCarran International Airport 07:15
        SANSan Diego International Airport 09:25
      • 5h 50m (55m)
      • 1 Stop LAS · Las Vegas 55m
      • Southwest Airlines (WN 1083)Boeing 737 800
        Southwest Airlines (WN 1301)Boeing 737 700
      • Southwest Airlines (WN 1083)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 05:35 STL
        10:40 SAN
        7Hrs, 05m 1 Stop (LAS)
      • STLSt Louis Lambert Intl Airport 05:35 - SAN 10:40 7h 05m 1 Stop (LAS) Las Vegas
      • STLSt Louis Lambert Intl Airport 05:35
        LASLas Vegas McCarran International Airport 09:25
      • LASLas Vegas McCarran International Airport 07:15
        SANSan Diego International Airport 10:40
      • 7h 05m (2h 10m)
      • 1 Stop LAS · Las Vegas 2h 10m
      • Southwest Airlines (WN 1083)Boeing 737 800
        Southwest Airlines (WN 3882)Boeing 737 700
      • Southwest Airlines (WN 1083)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 05:40 STL
        10:45 SAN
        7Hrs, 05m 1 Stop (DEN)
      • STLSt Louis Lambert Intl Airport 05:40 - SAN 10:45 7h 05m 1 Stop (DEN) Denver
      • STLSt Louis Lambert Intl Airport 05:40
        DENDenver Intl Airport 09:20
      • DENDenver Intl Airport 07:10
        SANSan Diego International Airport 10:45
      • 7h 05m (2h 10m)
      • 1 Stop DEN · Denver 2h 10m
      • Southwest Airlines (WN 474)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 5254)Boeing 737 800
      • Southwest Airlines (WN 474)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 10:55 PHX
        07:10 DEN
        7Hrs, 30m 1 Stop (SAN)
      • PHXPhoenix Sky Harbor Intl Airport 10:55 - DEN 07:10 7h 30m 1 Stop (SAN) San Diego
      • PHXPhoenix Sky Harbor Intl Airport 10:55
        STLSt Louis Lambert Intl Airport 05:40
      • SANSan Diego International Airport 11:10
        DENDenver Intl Airport 07:10
      • 7h 30m (1h 35m)
      • 1 Stop SAN · San Diego 1h 35m
      • Southwest Airlines (WN 1785)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 474)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 1785)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 05:40 STL
        11:55 SAN
        8Hrs, 15m 1 Stop (DAL)
      • STLSt Louis Lambert Intl Airport 05:40 - SAN 11:55 8h 15m 1 Stop (DAL) Dallas
      • STLSt Louis Lambert Intl Airport 05:40
        DALDallas/Fort Worth Love Field Airport 10:40
      • DALDallas/Fort Worth Love Field Airport 07:30
        SANSan Diego International Airport 11:55
      • 8h 15m (3h 10m)
      • 1 Stop DAL · Dallas 3h 10m
      • Southwest Airlines (WN 300)Boeing 737 700
        Southwest Airlines (WN 3008)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 300)
        • -
        • -
        • -
        • T
        • -
        • -
        • -
      • 05:45 STL
        11:55 SAN
        8Hrs, 10m 1 Stop (DAL)
      • STLSt Louis Lambert Intl Airport 05:45 - SAN 11:55 8h 10m 1 Stop (DAL) Dallas
      • STLSt Louis Lambert Intl Airport 05:45
        DALDallas/Fort Worth Love Field Airport 10:40
      • DALDallas/Fort Worth Love Field Airport 07:35
        SANSan Diego International Airport 11:55
      • 8h 10m (3h 05m)
      • 1 Stop DAL · Dallas 3h 05m
      • Southwest Airlines (WN 5)Boeing 737 700
        Southwest Airlines (WN 4494)Boeing 737 700
      • Southwest Airlines (WN 5)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 05:45 STL
        11:55 SAN
        8Hrs, 10m 1 Stop (PHX)
      • STLSt Louis Lambert Intl Airport 05:45 - SAN 11:55 8h 10m 1 Stop (PHX) Phoenix
      • STLSt Louis Lambert Intl Airport 05:45
        PHXPhoenix Sky Harbor Intl Airport 11:30
      • PHXPhoenix Sky Harbor Intl Airport 08:15
        SANSan Diego International Airport 11:55
      • 8h 10m (3h 15m)
      • 1 Stop PHX · Phoenix 3h 15m
      • Southwest Airlines (WN 3800)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 302)Boeing 737 700
      • Southwest Airlines (WN 3800)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 05:45 STL
        12:33 SAN
        8Hrs, 48m 1 Stop (ORD)
      • STLSt Louis Lambert Intl Airport 05:45 - SAN 12:33 8h 48m 1 Stop (ORD) Chicago
      • STLSt Louis Lambert Intl Airport 05:45
        ORDChicago O'Hare International Airport 10:05
      • ORDChicago O'Hare International Airport 07:09
        SANSan Diego International Airport 12:33
      • 8h 48m (2h 56m)
      • 1 Stop ORD · Chicago 2h 56m
      • American Airlines (AA 629)Boeing 737 800
        American Airlines (AA 2131)Boeing 737 800
      • American Airlines (AA 629)
        • M
        • T
        • W
        • -
        • -
        • S
        • S
      • 05:45 STL
        10:10 SAN
        6Hrs, 25m 1 Stop (LAS)
      • STLSt Louis Lambert Intl Airport 05:45 - SAN 10:10 6h 25m 1 Stop (LAS) Las Vegas
      • STLSt Louis Lambert Intl Airport 05:45
        LASLas Vegas McCarran International Airport 08:55
      • LASLas Vegas McCarran International Airport 07:25
        SANSan Diego International Airport 10:10
      • 6h 25m (1h 30m)
      • 1 Stop LAS · Las Vegas 1h 30m
      • Southwest Airlines (WN 1525)Boeing 737 700
        Southwest Airlines (WN 1486)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 1525)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 05:45 STL
        10:25 SAN
        6Hrs, 40m 1 Stop (MDW)
      • STLSt Louis Lambert Intl Airport 05:45 - SAN 10:25 6h 40m 1 Stop (MDW) Chicago
      • STLSt Louis Lambert Intl Airport 05:45
        MDWChicago Midway Airport 07:55
      • MDWChicago Midway Airport 06:55
        SANSan Diego International Airport 10:25
      • 6h 40m (1h)
      • 1 Stop MDW · Chicago 1h
      • Southwest Airlines (WN 367)Boeing 737 800
        Southwest Airlines (WN 1988)Boeing 737 700
      • Southwest Airlines (WN 367)
        • -
        • -
        • -
        • T
        • -
        • -
        • -
      • 05:45 STL
        10:45 SAN
        7Hrs, 00m 1 Stop (PHX)
      • STLSt Louis Lambert Intl Airport 05:45 - SAN 10:45 7h 1 Stop (PHX) Phoenix
      • STLSt Louis Lambert Intl Airport 05:45
        PHXPhoenix Sky Harbor Intl Airport 10:25
      • PHXPhoenix Sky Harbor Intl Airport 08:15
        SANSan Diego International Airport 10:45
      • 7h (2h 10m)
      • 1 Stop PHX · Phoenix 2h 10m
      • Southwest Airlines (WN 3800)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 2219)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 3800)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 05:45 STL
        11:10 SAN
        7Hrs, 25m 1 Stop (LAS)
      • STLSt Louis Lambert Intl Airport 05:45 - SAN 11:10 7h 25m 1 Stop (LAS) Las Vegas
      • STLSt Louis Lambert Intl Airport 05:45
        LASLas Vegas McCarran International Airport 09:55
      • LASLas Vegas McCarran International Airport 07:25
        SANSan Diego International Airport 11:10
      • 7h 25m (2h 30m)
      • 1 Stop LAS · Las Vegas 2h 30m
      • Southwest Airlines (WN 1525)Boeing 737 700
        Southwest Airlines (WN 1542)Boeing 737 700
      • Southwest Airlines (WN 1525)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 05:45 STL
        11:15 SAN
        7Hrs, 30m 1 Stop (DAL)
      • STLSt Louis Lambert Intl Airport 05:45 - SAN 11:15 7h 30m 1 Stop (DAL) Dallas
      • STLSt Louis Lambert Intl Airport 05:45
        DALDallas/Fort Worth Love Field Airport 08:35
      • DALDallas/Fort Worth Love Field Airport 07:35
        SANSan Diego International Airport 11:15
      • 7h 30m (1h)
      • 1 Stop DAL · Dallas 1h
      • Southwest Airlines (WN 5)Boeing 737 700
        Southwest Airlines (WN 422)Boeing 737 700
      • Southwest Airlines (WN 5)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 05:50 STL
        10:05 SAN
        6Hrs, 15m 1 Stop (LAS)
      • STLSt Louis Lambert Intl Airport 05:50 - SAN 10:05 6h 15m 1 Stop (LAS) Las Vegas
      • STLSt Louis Lambert Intl Airport 05:50
        LASLas Vegas McCarran International Airport 08:50
      • LASLas Vegas McCarran International Airport 07:30
        SANSan Diego International Airport 10:05
      • 6h 15m (1h 20m)
      • 1 Stop LAS · Las Vegas 1h 20m
      • Southwest Airlines (WN 197)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 4428)Boeing 737 700
      • Southwest Airlines (WN 197)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 05:50 STL
        10:45 SAN
        6Hrs, 55m 1 Stop (DEN)
      • STLSt Louis Lambert Intl Airport 05:50 - SAN 10:45 6h 55m 1 Stop (DEN) Denver
      • STLSt Louis Lambert Intl Airport 05:50
        DENDenver Intl Airport 09:20
      • DENDenver Intl Airport 07:15
        SANSan Diego International Airport 10:45
      • 6h 55m (2h 05m)
      • 1 Stop DEN · Denver 2h 05m
      • Southwest Airlines (WN 474)Boeing 737 700
        Southwest Airlines (WN 1535)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 474)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 05:50 STL
        11:30 SAN
        7Hrs, 40m 1 Stop (DAL)
      • STLSt Louis Lambert Intl Airport 05:50 - SAN 11:30 7h 40m 1 Stop (DAL) Dallas
      • STLSt Louis Lambert Intl Airport 05:50
        DALDallas/Fort Worth Love Field Airport 10:15
      • DALDallas/Fort Worth Love Field Airport 07:40
        SANSan Diego International Airport 11:30
      • 7h 40m (2h 35m)
      • 1 Stop DAL · Dallas 2h 35m
      • Southwest Airlines (WN 300)Boeing 737 700
        Southwest Airlines (WN 5221)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 300)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 05:50 STL
        11:45 SAN
        7Hrs, 55m 1 Stop (LAS)
      • STLSt Louis Lambert Intl Airport 05:50 - SAN 11:45 7h 55m 1 Stop (LAS) Las Vegas
      • STLSt Louis Lambert Intl Airport 05:50
        LASLas Vegas McCarran International Airport 10:30
      • LASLas Vegas McCarran International Airport 07:30
        SANSan Diego International Airport 11:45
      • 7h 55m (3h)
      • 1 Stop LAS · Las Vegas 3h
      • Southwest Airlines (WN 197)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 320)Boeing 737 700
      • Southwest Airlines (WN 197)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 05:50 STL
        12:10 SAN
        8Hrs, 20m 1 Stop (DEN)
      • STLSt Louis Lambert Intl Airport 05:50 - SAN 12:10 8h 20m 1 Stop (DEN) Denver
      • STLSt Louis Lambert Intl Airport 05:50
        DENDenver Intl Airport 10:45
      • DENDenver Intl Airport 07:15
        SANSan Diego International Airport 12:10
      • 8h 20m (3h 30m)
      • 1 Stop DEN · Denver 3h 30m
      • Southwest Airlines (WN 474)Boeing 737 700
        Southwest Airlines (WN 1087)Boeing 737 700
      • Southwest Airlines (WN 474)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 05:55 STL
        12:05 SAN
        8Hrs, 10m 1 Stop (DAL)
      • STLSt Louis Lambert Intl Airport 05:55 - SAN 12:05 8h 10m 1 Stop (DAL) Dallas
      • STLSt Louis Lambert Intl Airport 05:55
        DALDallas/Fort Worth Love Field Airport 10:50
      • DALDallas/Fort Worth Love Field Airport 07:45
        SANSan Diego International Airport 12:05
      • 8h 10m (3h 05m)
      • 1 Stop DAL · Dallas 3h 05m
      • Southwest Airlines (WN 300)Boeing 737 800
        Southwest Airlines (WN 3221)Boeing 737 700
      • Southwest Airlines (WN 300)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 06:00 STL
        12:20 SAN
        8Hrs, 20m 1 Stop (PHX)
      • STLSt Louis Lambert Intl Airport 06:00 - SAN 12:20 8h 20m 1 Stop (PHX) Phoenix
      • STLSt Louis Lambert Intl Airport 06:00
        PHXPhoenix Sky Harbor Intl Airport 12:05
      • PHXPhoenix Sky Harbor Intl Airport 08:30
        SANSan Diego International Airport 12:20
      • 8h 20m (3h 35m)
      • 1 Stop PHX · Phoenix 3h 35m
      • Southwest Airlines (WN 2991)Boeing 737 Max 8 Passenger
        Southwest Airlines (WN 2219)Boeing 737 700
      • Southwest Airlines (WN 2991)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 06:00 STL
        13:12 SAN
        9Hrs, 12m 1 Stop (EWR)
      • STLSt Louis Lambert Intl Airport 06:00 - SAN 13:12 9h 12m 1 Stop (EWR) New York City
      • STLSt Louis Lambert Intl Airport 06:00
        EWRNewark Liberty International Airport 10:05
      • EWRNewark Liberty International Airport 09:19
        SANSan Diego International Airport 13:12
      • 9h 12m (46m)
      • 1 Stop EWR · New York City 46m
      • United Airlines (UA 1834)Airbus
        United Airlines (UA 1626)Boeing 737 Max 8 Passenger
      • United Airlines (UA 1834)
        • -
        • -
        • -
        • -
        • F
        • -
        • -
      No Schedules Sorry, there are no schedules matching your filters. Try removing one. reset
      What’s the fastest flight time from Saint Louis to San Diego?

      The fastest flight time for direct flights from Saint Louis to San Diego is 4 hours . Check latest flight schedules & prices on Wego.

      What’s the most popular airline flying from Saint Louis to San Diego?

      The most popular airline flying from Saint Louis to San Diego is American Airlines. Find the latest flight deals on Wego.

      How far is San Diego from Saint Louis?

      The flight distance between Saint Louis and San Diego is 2512km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 05:00. The last flight of the day departs at 18:10. See the full list of flight times on Wego.

      How many airlines offer direct flights from Saint Louis to San Diego?

      There are 1 airlines that offer direct flights from Saint Louis to San Diego. Find out the list of airlines on Wego.

      All Airports in Saint Louis

      St Louis Lambert Intl Airport STL

      Popular Airlines flying from Saint Louis to San Diego

      American Airlines ‏()
      Frontier Airlines ‏()

      Popular Destinations from San Diego

      Popular Destinations from Saint Louis

      Popular Hotels in San Diego

      Hotels In Popular Destinations